Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615518 | 0.87 | ADRA1A (0.40) | ADRA1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9251285 | 0.77 | KDM4E (0.31) | ADRA1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8616402 | 0.74 | ADRA2A (0.49) | — | |
| SCHEMBL7928877 | 0.69 | CYP1A2 (0.42) | ADRA1AKDM4ES1PR1 | |
| SCHEMBL7917723 | 0.69 | S1PR1 (0.42) | ADRA1AS1PR1 | |
| SCHEMBL8989387 | 0.66 | ADRA1A (0.73) | ADRA1A | |
| SCHEMBL8615826 | 0.65 | KDM4E (0.45) | ADRA1AKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL11037944 | 0.65 | ADRA1A (0.71) | ADRA1A | |
| SCHEMBL11037972 | 0.63 | ADRA1A (0.73) | ADRA1A | |
| Hydrochloric Acid SCHEMBL11082003 | 0.62 | KDM4E (0.33) | ADRA1AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464859-A | Alpha adrenergic antagonist | ADIR ET COMPAGNIE (FR) | 1995-11-07 | — | — | US | disclosed |