Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251629 | 0.77 | ADRA1A (0.32) | KDM4EALDH1A1ADRA1AHPGDHSD17B10 | |
| SCHEMBL8620656 | 0.75 | ADRA2A (0.48) | — | |
| SCHEMBL8989387 | 0.65 | ADRA1A (0.73) | ADRA1A | |
| SCHEMBL8615826 | 0.64 | KDM4E (0.45) | KDM4EALDH1A1ADRA1AHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL11037944 | 0.64 | ADRA1A (0.71) | ADRA1A | |
| SCHEMBL8615518 | 0.62 | ADRA1A (0.40) | KDM4EALDH1A1ADRA1AHPGDHSD17B10 | |
| SCHEMBL11037972 | 0.62 | ADRA1A (0.73) | ADRA1A | |
| SCHEMBL11039763 | 0.60 | CHRM3 (0.57) | ADRA1A | |
| SCHEMBL29858876 | 0.60 | PDE4B (0.47) | — | |
| SCHEMBL11039127 | 0.60 | DRD2 (0.56) | ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464859-A | Alpha adrenergic antagonist | ADIR ET COMPAGNIE (FR) | 1995-11-07 | — | — | US | disclosed |