Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9251441 | 0.84 | LMNA (0.43) | HCAR3CDC25BNPC1CYP3A4HTT | |
| SCHEMBL9251399 | 0.79 | HCAR3 (0.64) | HCAR3CDC25BNPC1HTTMAPT | |
| SCHEMBL8900476 | 0.76 | HCAR3 (0.59) | HCAR3CDC25BHTTMAPT | |
| SCHEMBL9944988 | 0.73 | NPC1 (0.44) | HCAR3CDC25BNPC1CYP3A4HTT | |
| SCHEMBL9944775 | 0.73 | TDP1 (0.50) | HCAR3NPC1HTTMAPTALDH1A1 | |
| SCHEMBL2252717 | 0.72 | MEN1 (0.49) | HCAR3NPC1CYP3A4HTTMAPT | |
| SCHEMBL15323319 | 0.71 | PDGFRB (0.49) | HCAR3CDC25BHTTMAPTALDH1A1 | |
| SCHEMBL9899392 | 0.71 | MAPT (0.50) | HCAR3NPC1CYP3A4HTTMAPT | |
| SCHEMBL9247590 | 0.71 | NPC1 (0.50) | NPC1CYP3A4HTTMAPTALDH1A1 | |
| SCHEMBL28444583 | 0.70 | APEX1 (0.48) | NPC1CYP3A4MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |