Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258611 | 0.80 | CYP19A1 (0.41) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7489674 | 0.78 | CA1 (0.46) | MEN1KMT2AL3MBTL1HPGDALDH1A1 | |
| SCHEMBL9251887 | 0.77 | CYP19A1 (0.43) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9101266 | 0.73 | MAPT (0.41) | NPC1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL11574544 | 0.72 | ALDH1A1 (0.41) | SMN1; SMN2MEN1KMT2ACYP19A1ALDH1A1 | |
| SCHEMBL6071101 | 0.71 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8102819 | 0.71 | CYP1A2 (0.43) | L3MBTL1HPGDALDH1A1MAPTGAA | |
| SCHEMBL30057200 | 0.69 | MAPT (0.44) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8036000 | 0.68 | KDM4E (0.46) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7552122 | 0.68 | NFE2L2 (0.43) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5429774-A | FOR USE IN PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 1995-07-04 | — | — | US | disclosed |