Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753801 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL27908231 | 0.78 | CHRNB2 (0.49) | — | |
| SCHEMBL6599138 | 0.72 | SLC18A3 (0.47) | ALDH1A1LMNAMAPTSLC18A3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9366640 | 0.72 | TACR1 (0.45) | ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL6599141 | 0.71 | HRH3 (0.43) | ALDH1A1LMNAPOLBMAPTSLC18A3 | |
| SCHEMBL1581647 | 0.70 | SLC18A3 (0.48) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL28996248 | 0.69 | MAPT (0.45) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL29068350 | 0.68 | CYP1A2 (0.57) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL7036663 | 0.68 | HRH3 (0.43) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL2651147 | 0.67 | SLC18A3 (0.60) | ALDH1A1LMNAPOLBMAPTSLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648220-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA, Jyoti (SE) | 1995-04-19 | — | — | EP | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |