Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256634 | 0.96 | KMT2A (0.54) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL9247297 | 0.91 | KMT2A (0.52) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL9253569 | 0.82 | DRD2 (0.66) | KMT2ADRD2 | |
| SCHEMBL7731150 | 0.81 | FAAH (0.59) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL7227360 | 0.81 | MCHR1 (0.59) | MCHR1 | |
| SCHEMBL9253841 | 0.78 | ACHE (0.70) | MCHR1 | |
| SCHEMBL8132896 | 0.77 | ACHE (0.48) | — | |
| SCHEMBL7227265 | 0.76 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL9249556 | 0.75 | BCHE (0.46) | DRD2 | |
| SCHEMBL7736003 | 0.75 | MEN1 (0.48) | KMT2AMEN1CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441967-A | Treating cerebral edema; anticholinesterase or brain function-improving agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-15 | — | — | US | disclosed |
| CN-1024548-C | Cyclic amine compounds and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-05-18 | — | — | CN | disclosed |
| US-5294625-A | 1-benzyl,4-((4-dialkylaminophenyl)carbonyl)piperidines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0378207-B1 | CYCLIC AMINE COMPOUNDS AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5177087-A | Cerebral edema, cholinesterase inhibitor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| CN-1053231-A | Cyclic amine compound and uses thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-07-24 | — | — | CN | disclosed |
| EP-0378207-A1 | Cyclic amine compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-18 | — | — | EP | disclosed |