Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27364429 | 0.83 | OPRM1 (0.51) | ALDH1A1OPRM1 | |
| Hydrochloric Acid SCHEMBL9775427 | 0.80 | LMNA (0.60) | ALDH1A1OPRD1TDP1CACNA2D1CACNA1B | |
| SCHEMBL3391962 | 0.78 | CACNA2D1 (0.61) | ALDH1A1MEN1POLBKMT2AOPRD1 | |
| SCHEMBL9091641 | 0.76 | TDP1 (0.66) | ALDH1A1MEN1KMT2AOPRD1TDP1 | |
| Hydrochloric Acid SCHEMBL9775428 | 0.74 | OPRD1 (0.54) | MEN1KMT2AOPRD1CACNA2D1CACNA1B | |
| SCHEMBL8371748 | 0.74 | OPRD1 (0.67) | ALDH1A1MEN1KMT2AOPRD1TDP1 | |
| SCHEMBL11039741 | 0.74 | HRH1 (0.60) | ALDH1A1MEN1KMT2AOPRD1TDP1 | |
| SCHEMBL9181170 | 0.74 | DRD3 (0.63) | OPRD1TDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL28523059 | 0.73 | KMT2A (0.56) | ALDH1A1MEN1KMT2AOPRD1CACNA2D1 | |
| SCHEMBL9050321 | 0.72 | ALDH1A1 (0.44) | ALDH1A1POLBLMNAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |