Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256707 | 0.91 | OPRM1 (0.43) | OPRM1OPRD1NPC1RAB9AALDH1A1 | |
| SCHEMBL9253634 | 0.81 | SETD7 (0.43) | NPC1RAB9AALDH1A1LMNASETD7 | |
| SCHEMBL13437754 | 0.81 | SETD7 (0.66) | OPRM1OPRD1NPC1RAB9AALDH1A1 | |
| SCHEMBL9038594 | 0.78 | HTR2A (0.53) | OPRM1OPRD1ALDH1A1LMNASETD7 | |
| SCHEMBL9249498 | 0.76 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1LMNASETD7 | |
| SCHEMBL9257091 | 0.76 | OPRM1 (0.44) | OPRM1OPRD1NPC1RAB9AALDH1A1 | |
| SCHEMBL13437764 | 0.72 | SETD7 (0.54) | OPRM1OPRD1RAB9AALDH1A1SETD7 | |
| SCHEMBL27508978 | 0.72 | OPRM1 (0.45) | OPRM1OPRD1ALDH1A1SETD7HTR2A | |
| SCHEMBL13437756 | 0.70 | SETD7 (0.54) | OPRM1OPRD1ALDH1A1SETD7KDM4E | |
| SCHEMBL13462407 | 0.70 | OPRM1 (0.57) | OPRM1OPRD1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |