Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253253 | 0.90 | CES2 (0.42) | ALDH1A1LMNACES2CES1HPGD | |
| SCHEMBL9038594 | 0.82 | HTR2A (0.53) | ALDH1A1SETD7LMNACHRM2CYP2D6 | |
| SCHEMBL9253634 | 0.81 | SETD7 (0.43) | ALDH1A1SETD7LMNACHRM2CYP2D6 | |
| SCHEMBL9257091 | 0.80 | OPRM1 (0.44) | ALDH1A1SETD7LMNACHRM2CYP2D6 | |
| SCHEMBL9253170 | 0.76 | OPRM1 (0.48) | ALDH1A1SETD7LMNACHRM2CYP2D6 | |
| SCHEMBL9253261 | 0.71 | OPRM1 (0.42) | SETD7LMNACES2CES1NPC1 | |
| SCHEMBL9256562 | 0.69 | SMN1; SMN2 (0.40) | ALDH1A1CHRM3SMN1; SMN2NPC1HPGD | |
| SCHEMBL11035757 | 0.69 | HRH1 (0.48) | HTR2AHRH1HTR2BKCNH2HPGD | |
| SCHEMBL9258377 | 0.68 | CES2 (0.42) | ALDH1A1CES2CES1NPC1GAA | |
| SCHEMBL1774131 | 0.66 | SETD7 (0.64) | ALDH1A1SETD7LMNACHRM2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | claimed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | claimed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |