Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256562 | 0.89 | SMN1; SMN2 (0.40) | CHRM3NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9038594 | 0.83 | HTR2A (0.53) | SETD7LMNACHRM2CYP2D6CHRM1 | |
| SCHEMBL9257091 | 0.81 | OPRM1 (0.44) | SETD7LMNACHRM2CYP2D6CHRM1 | |
| SCHEMBL9249498 | 0.81 | ALDH1A1 (0.40) | SETD7LMNACHRM2CYP2D6CHRM1 | |
| SCHEMBL9253170 | 0.81 | OPRM1 (0.48) | SETD7LMNACHRM2CYP2D6CHRM1 | |
| SCHEMBL9258377 | 0.69 | CES2 (0.42) | NPC1HPGDALDH1A1ERCC5FEN1 | |
| SCHEMBL1774131 | 0.68 | SETD7 (0.64) | SETD7LMNACHRM2CYP2D6CHRM1 | |
| SCHEMBL430940 | 0.66 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL336772 | 0.66 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL9613657 | 0.66 | SETD7 (0.61) | SETD7SMN1; SMN2HPGDALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |