Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253170 | 0.91 | OPRM1 (0.48) | OPRM1OPRD1CTSDHTTTSHR | |
| SCHEMBL9256562 | 0.78 | SMN1; SMN2 (0.40) | HTTSMN1; SMN2TSHRALDH1A1NPC1 | |
| SCHEMBL13437756 | 0.78 | SETD7 (0.54) | OPRM1OPRD1HTTTP53ALDH1A1 | |
| SCHEMBL13437754 | 0.70 | SETD7 (0.66) | OPRM1OPRD1HTTTSHRALDH1A1 | |
| SCHEMBL9253634 | 0.69 | SETD7 (0.43) | SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL9579269 | 0.69 | HTT (0.72) | HTTCA1CA2CA12CA7 | |
| SCHEMBL157181 | 0.68 | CA1 (0.60) | CTSDHTTCA1CA2CA12 | |
| SCHEMBL13437764 | 0.68 | SETD7 (0.54) | OPRM1OPRD1HTTTSHRALDH1A1 | |
| SCHEMBL3277622 | 0.66 | CA1 (0.57) | CTSDHTTCA1CA2CA12 | |
| SCHEMBL2119268 | 0.66 | CA1 (0.57) | CTSDHTTCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |