Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 6/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473324 | 0.86 | CYP11B2 (0.53) | SMN1; SMN2LMNAHTTPKMALDH1A1 | |
| SCHEMBL9250447 | 0.86 | HTT (0.57) | SMN1; SMN2LMNAHTTPKMALDH1A1 | |
| SCHEMBL9281018 | 0.76 | CYP11B2 (0.50) | SMN1; SMN2LMNAHTTPKMALDH1A1 | |
| SCHEMBL27330067 | 0.71 | CYP11B2 (0.46) | SMN1; SMN2LMNAHTTPKMALDH1A1 | |
| SCHEMBL27337797 | 0.71 | ALDH1A1 (0.49) | SMN1; SMN2LMNAHTTPKMALDH1A1 | |
| SCHEMBL9253628 | 0.66 | HTT (0.50) | SMN1; SMN2LMNAHTTPKMALDH1A1 | |
| SCHEMBL9258593 | 0.66 | GAA (0.41) | SMN1; SMN2LMNAMAPK1HTTALDH1A1 | |
| SCHEMBL9256497 | 0.64 | CYP11B2 (0.48) | SMN1; SMN2LMNAHTTPKMALDH1A1 | |
| SCHEMBL9471997 | 0.62 | RAB9A (0.42) | MAPTSMN1; SMN2RAB9ALMNAMAPK1 | |
| SCHEMBL27330065 | 0.62 | CYP11B2 (0.46) | MAPTSMN1; SMN2TDP1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425283-B1 | Novel triazolyl hydrazide derivatives and process for their preparation | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-05-10 | — | — | EP | disclosed |
| US-5225410-A | Antiangina, antiulcer agents | EGIS GYOGYSZERGYAR (HU) | 1993-07-06 | — | — | US | disclosed |