Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ITGAM | P11215 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259393 | 0.88 | ITGB3 (0.39) | DGAT1ITGB3ITGA2BCYP2C9F10 | |
| SCHEMBL9258178 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL9053167 | 0.77 | ACHE (0.41) | DGAT1ITGB3ITGA2B | |
| SCHEMBL9053164 | 0.77 | ACHE (0.41) | DGAT1ITGB3ITGA2B | |
| SCHEMBL9250975 | 0.73 | FFAR1 (0.40) | DGAT1 | |
| SCHEMBL9254802 | 0.72 | ITGB3 (0.42) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL8949275 | 0.70 | ITGB3 (0.46) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL9259330 | 0.70 | ITGB3 (0.42) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL9256974 | 0.70 | ITGB3 (0.51) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL9253132 | 0.70 | ITGB3 (0.51) | ITGB3ITGA2BF10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |