Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 8/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 5/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254757 | 0.90 | ITGB3 (0.36) | TMPRSS15MAPTF10F2PRSS1 | |
| SCHEMBL8863938 | 0.84 | TMPRSS15 (0.36) | TMPRSS15MAPTF10F2PRSS1 | |
| SCHEMBL9258214 | 0.82 | TMPRSS15 (0.39) | TMPRSS15F10F2PRSS1 | |
| SCHEMBL9259335 | 0.81 | TMPRSS15 (0.41) | TMPRSS15MAPTF10F2PRSS1 | |
| SCHEMBL9254755 | 0.80 | MAP4K4 (0.38) | TMPRSS15F10F2PRSS1F9 | |
| SCHEMBL9254271 | 0.80 | SYK (0.33) | TMPRSS15F10F2PRSS1 | |
| SCHEMBL9251133 | 0.79 | TMPRSS15 (0.41) | TMPRSS15F10F2PRSS1ITGB3 | |
| SCHEMBL9251525 | 0.79 | MIF (0.37) | TMPRSS15ITGB3ITGA2B | |
| SCHEMBL9258001 | 0.78 | TMPRSS15 (0.36) | TMPRSS15MAPTF10F2PRSS1 | |
| SCHEMBL9256201 | 0.77 | TMPRSS15 (0.35) | TMPRSS15F10F2PRSS1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |