Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | ADH5 | P11766 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254271 | 0.90 | SYK (0.33) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL9251004 | 0.89 | PRSS1 (0.37) | ITGB3ITGA2BPRSS1F10F2 | |
| SCHEMBL9256872 | 0.89 | TMPRSS15 (0.35) | ITGB3ITGA2BPRSS1F10F2 | |
| SCHEMBL9251805 | 0.85 | PDK1 (0.33) | FFAR1PDK1 | |
| SCHEMBL9568440 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BPRSS1F10F2 | |
| SCHEMBL9258452 | 0.81 | PRSS1 (0.36) | PRSS1F10F2 | |
| SCHEMBL9252815 | 0.80 | TMPRSS15 (0.39) | PRSS1F10F2 | |
| SCHEMBL9254757 | 0.79 | ITGB3 (0.36) | ITGB3ITGA2BFFAR1PRSS1F10 | |
| SCHEMBL9253978 | 0.79 | ITGB3 (0.37) | ITGB3ITGA2BPRSS1F10F2 | |
| SCHEMBL9255073 | 0.76 | PIK3CA (0.32) | F10F2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |