Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.32 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258452 | 0.92 | PRSS1 (0.36) | PRSS1PLAUF10F2CSNK2A1 | |
| SCHEMBL9257720 | 0.89 | ITGB3 (0.33) | PRSS1F10F2ITGB3ITGA2B | |
| SCHEMBL9256872 | 0.87 | TMPRSS15 (0.35) | PRSS1F10F2ITGB3ITGA2B | |
| SCHEMBL9254271 | 0.83 | SYK (0.33) | PRSS1F10F2TMPRSS15 | |
| SCHEMBL9568440 | 0.83 | ITGB3 (0.39) | PRSS1F10F2ITGB3ITGA2B | |
| SCHEMBL9252815 | 0.82 | TMPRSS15 (0.39) | PRSS1F10F2TMPRSS15 | |
| SCHEMBL9251805 | 0.81 | PDK1 (0.33) | — | |
| SCHEMBL9259497 | 0.78 | KDM5A (0.35) | PRSS1F10F2TMPRSS15 | |
| SCHEMBL8863938 | 0.77 | TMPRSS15 (0.36) | PRSS1F10F2NPC1RAB9A | |
| SCHEMBL9253978 | 0.77 | ITGB3 (0.37) | PRSS1F10F2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |