Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ITGAM | P11215 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250591 | 0.88 | MIF (0.43) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9568440 | 0.82 | ITGB3 (0.39) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9251266 | 0.80 | ITGB3 (0.40) | ITGB3ITGA2BPRSS1TMPRSS15ITGB2 | |
| SCHEMBL9247213 | 0.80 | ITGB3 (0.39) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9257188 | 0.79 | NQO2 (0.38) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9250761 | 0.78 | F2 (0.40) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9255129 | 0.78 | ITGB3 (0.36) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9253978 | 0.76 | ITGB3 (0.37) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9250967 | 0.75 | MAP4K4 (0.41) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9248487 | 0.75 | AGER (0.38) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |