Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SPNS2 | Q8IVW8 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257112 | 0.91 | TLR8 (0.36) | AGERTLR8NPC1RAB9ANFKB1 | |
| SCHEMBL9247213 | 0.86 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL9250761 | 0.85 | F2 (0.40) | ITGB3ITGA2B | |
| SCHEMBL9255129 | 0.81 | ITGB3 (0.36) | ITGB3ITGA2B | |
| SCHEMBL9257188 | 0.81 | NQO2 (0.38) | ITGB3ITGA2B | |
| SCHEMBL9568422 | 0.78 | F2 (0.37) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL9256892 | 0.76 | P4HTM (0.38) | NPC1RAB9ASMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL9568440 | 0.76 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL9280389 | 0.76 | ITGB3 (0.35) | NPC1RAB9AITGB3ITGA2BALDH1A1 | |
| SCHEMBL9254897 | 0.75 | ITGB3 (0.45) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |