Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250808 | 0.90 | ITGB3 (0.36) | ITGB3ITGA2BPRSS1TMPRSS15TP53 | |
| SCHEMBL9247213 | 0.87 | ITGB3 (0.39) | ITGB3ITGA2BNQO2PRSS1TMPRSS15 | |
| SCHEMBL9257188 | 0.83 | NQO2 (0.38) | ITGB3ITGA2BNQO2PRSS1TMPRSS15 | |
| SCHEMBL9248487 | 0.81 | AGER (0.38) | ITGB3ITGA2B | |
| SCHEMBL9250761 | 0.81 | F2 (0.40) | ITGB3ITGA2BNQO2PRSS1TMPRSS15 | |
| SCHEMBL9256892 | 0.79 | P4HTM (0.38) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL9254897 | 0.78 | ITGB3 (0.45) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9280389 | 0.77 | ITGB3 (0.35) | ITGB3ITGA2BNQO2PRSS1TMPRSS15 | |
| SCHEMBL9568440 | 0.77 | ITGB3 (0.39) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9259191 | 0.76 | NQO2 (0.38) | ITGB3ITGA2BNQO2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |