Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252483 | 0.90 | ITGB3 (0.44) | ITGB3ITGA2BCHEK2BRD4ALOX15 | |
| SCHEMBL9255901 | 0.87 | ITGB3 (0.39) | ITGB3ITGA2BCHEK2BRD4LMNA | |
| SCHEMBL9251738 | 0.85 | PADI4 (0.43) | ITGB3ITGA2BMAP4K4 | |
| SCHEMBL9251783 | 0.79 | TMPRSS15 (0.45) | ITGB3ITGA2BCHEK2LMNAKDM4E | |
| SCHEMBL9253758 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL9251234 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BBRD4ALOX15F10 | |
| Hydrochloric Acid SCHEMBL8949253 | 0.77 | NPC1 (0.45) | ITGB3ITGA2BKDM4EALDH1A1POLB | |
| SCHEMBL9255399 | 0.75 | SCN9A (0.42) | ITGB3ITGA2BCHEK2F2F10 | |
| Hydrochloric Acid SCHEMBL8714344 | 0.72 | KDM1A (0.54) | ITGB3ITGA2BKDM1ALMNAKDM4E | |
| SCHEMBL9251312 | 0.70 | TMPRSS15 (0.40) | ITGB3ITGA2BMAPTSMN1; SMN2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |