Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255901 | 0.91 | ITGB3 (0.39) | ITGB3ITGA2BBRD4ALOX15F10 | |
| SCHEMBL9252483 | 0.86 | ITGB3 (0.44) | ITGB3ITGA2BBRD4NQO2ALOX15 | |
| SCHEMBL9253758 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL9255246 | 0.78 | ITGB3 (0.35) | ITGB3ITGA2BBRD4ALOX15F10 | |
| SCHEMBL9251783 | 0.78 | TMPRSS15 (0.45) | ITGB3ITGA2BNQO2F10 | |
| SCHEMBL9251738 | 0.73 | PADI4 (0.43) | ITGB3ITGA2B | |
| SCHEMBL9255399 | 0.68 | SCN9A (0.42) | ITGB3ITGA2BF10 | |
| SCHEMBL8949226 | 0.68 | ITGB3 (0.58) | ITGB3ITGA2B | |
| SCHEMBL9254810 | 0.65 | VCP (0.41) | ITGB3ITGA2B | |
| SCHEMBL9252818 | 0.65 | ADORA3 (0.41) | ITGB3ITGA2BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |