Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.39 |
| ▸ | F10 | P00742 | 7/20 | 0.33 |
| ▸ | F2 | P00734 | 7/20 | 0.33 |
| ▸ | PLG | P00747 | 4/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251234 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BF10BRD4ALOX15 | |
| SCHEMBL9255246 | 0.87 | ITGB3 (0.35) | ITGB3ITGA2BF10F2PLG | |
| SCHEMBL9251738 | 0.82 | PADI4 (0.43) | ITGB3ITGA2B | |
| SCHEMBL9252483 | 0.78 | ITGB3 (0.44) | ITGB3ITGA2BBRD4CHEK2ALOX15 | |
| SCHEMBL9253758 | 0.75 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL9251783 | 0.74 | TMPRSS15 (0.45) | ITGB3ITGA2BF10F2CHEK2 | |
| SCHEMBL9255399 | 0.71 | SCN9A (0.42) | ITGB3ITGA2BF10F2PLG | |
| Hydrochloric Acid SCHEMBL8949290 | 0.70 | ITGB3 (0.46) | ITGB3ITGA2BF10F2 | |
| SCHEMBL9251312 | 0.66 | TMPRSS15 (0.40) | ITGB3ITGA2BF10SMN1; SMN2 | |
| SCHEMBL9255137 | 0.66 | TMPRSS15 (0.41) | ITGB3ITGA2BF10F2CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |