Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253758 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL9252483 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2BCHEK2NQO2 | |
| SCHEMBL9251738 | 0.83 | PADI4 (0.43) | TMPRSS15ITGB3ITGA2B | |
| SCHEMBL9252818 | 0.80 | ADORA3 (0.41) | TMPRSS15ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL9255246 | 0.79 | ITGB3 (0.35) | ITGB3ITGA2BLMNAHTTKDM4E | |
| SCHEMBL9254810 | 0.78 | VCP (0.41) | ITGB3ITGA2B | |
| SCHEMBL9256431 | 0.78 | ITGB3 (0.38) | TMPRSS15ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL9251234 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BF10NQO2 | |
| SCHEMBL9255399 | 0.76 | SCN9A (0.42) | TMPRSS15ITGB3ITGA2BF10CHEK2 | |
| SCHEMBL9255901 | 0.74 | ITGB3 (0.39) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |