Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25336398 | 0.82 | KLK7 (0.56) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL4561864 | 0.81 | HDAC2 (0.54) | HDAC2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL4561508 | 0.78 | POLB (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2KLK7 | |
| SCHEMBL11382012 | 0.76 | MAPT (0.54) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL29006055 | 0.76 | HDAC2 (0.58) | HDAC2MEN1KMT2AHPGDTSHR | |
| SCHEMBL11089459 | 0.75 | KLK7 (0.52) | HDAC2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL7638637 | 0.75 | LMNA (0.55) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL1754848 | 0.74 | POLB (0.55) | HDAC2MEN1KMT2AHPGDTSHR | |
| SCHEMBL5509053 | 0.74 | ALDH1A1 (0.52) | HDAC2MEN1KMT2AALDH1A1KLK7 | |
| SCHEMBL11642274 | 0.74 | HDAC2 (0.62) | HDAC2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649418-A1 | 7-(2-AMINOETHYL)-BENZOTHIAZOLONES | Astra Pharmaceuticals Limited (GB) | 1995-04-26 | — | — | EP | disclosed |
| WO-1993024473-A1 | 7-(2-AMINOETHYL)-BENZOTHIAZOLONES | FISONS PLC (GB) | 1993-12-09 | — | — | WO | disclosed |