Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257252 | 0.88 | GRM5 (0.36) | ALDH1A1LMNAGAASMN1; SMN2HSD11B1 | |
| SCHEMBL9261971 | 0.87 | HSD11B1 (0.56) | ALDH1A1LMNAGAASMN1; SMN2POLB | |
| SCHEMBL9254614 | 0.85 | MGLL (0.43) | ALDH1A1LMNAMGLL | |
| SCHEMBL9257899 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNAMGLL | |
| SCHEMBL9257657 | 0.78 | HPGD (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9261700 | 0.77 | MGLL (0.49) | ALDH1A1LMNAGAASMN1; SMN2POLB | |
| SCHEMBL9257855 | 0.77 | KDM4E (0.50) | ALDH1A1L3MBTL1KDM4EMGLL | |
| SCHEMBL9257887 | 0.76 | MGLL (0.41) | ALDH1A1HSD11B1KDM4EMGLL | |
| SCHEMBL9261899 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL9254577 | 0.76 | SMN1; SMN2 (0.51) | CA12CA2CA9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |