Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 4/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256417 | 0.77 | CA12 (0.43) | KDM4EALDH1A1L3MBTL1MGLL | |
| SCHEMBL9254577 | 0.76 | SMN1; SMN2 (0.51) | KDM4EALDH1A1HSD17B10PKML3MBTL1 | |
| SCHEMBL9261899 | 0.76 | ALDH1A1 (0.55) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL9257657 | 0.76 | HPGD (0.47) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL9263933 | 0.76 | MEN1 (0.48) | KDM4EALDH1A1HSD17B10CYP1A2CYP2C19 | |
| SCHEMBL9253329 | 0.75 | SCD5 (0.46) | ALDH1A1L3MBTL1KMT2AMGLL | |
| SCHEMBL9261873 | 0.75 | MEN1 (0.53) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9254614 | 0.73 | MGLL (0.43) | ALDH1A1KMT2AMGLL | |
| SCHEMBL9253316 | 0.73 | LTB4R (0.56) | CYP2C19MGLL | |
| SCHEMBL9257252 | 0.70 | GRM5 (0.36) | ALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |