Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261873 | 0.89 | MEN1 (0.53) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9253316 | 0.83 | LTB4R (0.56) | MGLLGRIN2B | |
| SCHEMBL9261899 | 0.80 | ALDH1A1 (0.55) | SMN1; SMN2MEN1LMNATSHRMAPK1 | |
| SCHEMBL9253329 | 0.79 | SCD5 (0.46) | KMT2AL3MBTL1ALDH1A1CA12CA2 | |
| SCHEMBL9257855 | 0.76 | KDM4E (0.50) | MEN1TSHRKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9256417 | 0.76 | CA12 (0.43) | SMN1; SMN2LMNAMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL9257657 | 0.75 | HPGD (0.47) | SMN1; SMN2MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL9261915 | 0.73 | KDM4E (0.52) | SMN1; SMN2MEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL4486386 | 0.73 | KDM4E (0.78) | SMN1; SMN2MEN1LMNATSHRMAPK1 | |
| SCHEMBL9254614 | 0.72 | MGLL (0.43) | LMNAKMT2AALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |