Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253634 | 0.89 | SETD7 (0.43) | SMN1; SMN2HPGDALDH1A1ERCC5FEN1 | |
| SCHEMBL9253253 | 0.78 | CES2 (0.42) | HTTHPGDALDH1A1CYP2C19ELANE | |
| SCHEMBL9258377 | 0.78 | CES2 (0.42) | HTTHPGDALDH1A1TSHRERCC5 | |
| SCHEMBL9613657 | 0.74 | SETD7 (0.61) | SMN1; SMN2HTTHPGDALDH1A1CYP3A4 | |
| SCHEMBL14707030 | 0.73 | ALDH1A1 (0.40) | SMN1; SMN2HTTALDH1A1NPC1RAB9A | |
| SCHEMBL9253170 | 0.70 | OPRM1 (0.48) | HTTALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL9257091 | 0.69 | OPRM1 (0.44) | SMN1; SMN2HTTALDH1A1ERCC5FEN1 | |
| SCHEMBL18469361 | 0.67 | RAB9A (0.42) | SMN1; SMN2HTTHPGDALDH1A1CYP3A4 | |
| SCHEMBL2038760 | 0.65 | ACHE (0.53) | SMN1; SMN2HTTHPGDALDH1A1TSHR | |
| SCHEMBL39369 | 0.63 | TSHR (0.50) | SMN1; SMN2HTTHPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |