Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.52 |
| ▸ | UBE2M | P61081 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260171 | 0.90 | UBE2M (0.64) | DCUN1D1UBE2MALDH1A1MEN1KMT2A | |
| SCHEMBL9260667 | 0.85 | ALDH1A1 (0.54) | DCUN1D1UBE2MALDH1A1MAPTROCK2 | |
| SCHEMBL9256017 | 0.85 | ALDH1A1 (0.66) | DCUN1D1UBE2MALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL9257544 | 0.84 | SLC6A9 (0.59) | DCUN1D1UBE2MALDH1A1ROCK2SMN1; SMN2 | |
| SCHEMBL9261691 | 0.84 | ALDH1A1 (0.53) | DCUN1D1UBE2MALDH1A1MAPTROCK2 | |
| SCHEMBL9257297 | 0.84 | DCUN1D1 (0.56) | DCUN1D1UBE2MALDH1A1MAPTROCK2 | |
| SCHEMBL9255834 | 0.84 | ALDH1A1 (0.53) | DCUN1D1UBE2MALDH1A1EPHX1MAPT | |
| SCHEMBL9265728 | 0.84 | AGER (0.56) | DCUN1D1UBE2MALDH1A1ROCK2SMN1; SMN2 | |
| SCHEMBL9255607 | 0.84 | ALDH1A1 (0.53) | DCUN1D1UBE2MALDH1A1MAPTROCK2 | |
| Hydrochloric Acid SCHEMBL9262873 | 0.83 | ALDH1A1 (0.52) | DCUN1D1UBE2MALDH1A1EPHX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5384425-A | Diurea derivatives useful as medicaments and processes for the preparation thereof | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-01-24 | — | — | US | disclosed |
| EP-0325397-B1 | DIUREA DERIVATIVES USEFUL AS MEDICAMENTS AND PROCESSES FOR THE PREPARATION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5227492-A | Anticholesterol agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| US-5166429-A | Enzyme inhibitors of acylcoenzyme A cholesterol transferase as anticholesterol agents or antideposit agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| US-5091419-A | Anticholesterol agent | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |