Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | DRD5 | P21918 | 2/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044229 | 0.77 | LTA4H (0.60) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL1043285 | 0.76 | ADRA2A (0.65) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL1042245 | 0.76 | DRD2 (0.61) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL9260735 | 0.76 | POLB (0.76) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL1871710 | 0.75 | ADRA2A (0.68) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL5022446 | 0.74 | ABCB1 (0.55) | ALDH1A1MAPTDRD2ABCB1LMNA | |
| SCHEMBL7937213 | 0.74 | HTR1A (0.71) | MAPTDRD2LMNADRD4DRD3 | |
| SCHEMBL29791109 | 0.71 | ADRA2A (0.60) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL2545665 | 0.71 | ADRA2A (0.60) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL2545666 | 0.71 | ADRA2A (0.60) | DRD2ADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |