Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ME2 | P23368 | 1/20 | 0.46 |
| ▸ | ME1 | P48163 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254709 | 0.84 | POLB (0.53) | POLBSMN1; SMN2GAAMAPK1MAPT | |
| SCHEMBL9259654 | 0.80 | POLB (0.53) | POLBSMN1; SMN2GAAMAPK1MAPT | |
| SCHEMBL9257650 | 0.76 | ALDH1A1 (0.50) | POLBSMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL14683495 | 0.74 | POLB (0.78) | POLBSMN1; SMN2GAAMAPK1MAPT | |
| SCHEMBL9259044 | 0.72 | KMT2A (0.61) | POLBSMN1; SMN2GAAMAPK1LMNA | |
| SCHEMBL2548219 | 0.72 | MAPK1 (0.71) | POLBSMN1; SMN2GAAMAPK1MAPT | |
| SCHEMBL9256464 | 0.71 | KMT2A (0.59) | POLBSMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL21198198 | 0.71 | CYP3A4 (0.47) | POLBSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL9255239 | 0.71 | DRD2 (0.49) | POLB | |
| SCHEMBL9261702 | 0.70 | POLB (0.70) | POLBSMN1; SMN2GAAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |