Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261440 | 0.85 | RAB9A (0.62) | RAB9ASMN1; SMN2POLBALDH1A1FKBP1A | |
| SCHEMBL9257699 | 0.76 | SMN1; SMN2 (0.53) | RAB9ASMN1; SMN2POLBALDH1A1FKBP1A | |
| SCHEMBL11271699 | 0.71 | NOTUM (0.63) | RAB9ASMN1; SMN2POLBALDH1A1FKBP1A | |
| SCHEMBL30070271 | 0.71 | MEN1 (0.63) | RAB9ASMN1; SMN2POLBALDH1A1FKBP1A | |
| SCHEMBL29551592 | 0.70 | ALDH1A1 (0.60) | SMN1; SMN2POLBALDH1A1FKBP1AMEN1 | |
| SCHEMBL9260528 | 0.70 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2POLBALDH1A1FKBP1A | |
| SCHEMBL8327592 | 0.70 | FKBP1A (1.00) | RAB9ASMN1; SMN2POLBALDH1A1FKBP1A | |
| SCHEMBL23279539 | 0.70 | ALDH1A1 (0.48) | POLBALDH1A1FKBP1AKDM4EHPGD | |
| SCHEMBL24658483 | 0.69 | GAA (0.61) | RAB9ASMN1; SMN2POLBFKBP1AKDM4E | |
| SCHEMBL10058128 | 0.69 | ITGB3 (0.52) | RAB9ASMN1; SMN2POLBALDH1A1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |