Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263478 | 0.95 | XDH (0.59) | XDHALDH1A1GAATRPC6DHODH | |
| SCHEMBL9271100 | 0.88 | ALDH1A1 (0.48) | XDHALDH1A1GAADHODHMAPT | |
| SCHEMBL9268068 | 0.86 | ALDH1A1 (0.43) | XDHALDH1A1GAATRPC6DHODH | |
| SCHEMBL1752782 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2APDE4A | |
| SCHEMBL9186302 | 0.84 | XDH (0.47) | XDHALDH1A1GAADHODHFPR2 | |
| SCHEMBL9325535 | 0.83 | FPR2 (0.47) | ALDH1A1TRPC6FPR2MAPTMEN1 | |
| SCHEMBL9267049 | 0.82 | PDE4A (0.43) | ALDH1A1FPR2MAPTMEN1KMT2A | |
| SCHEMBL9271648 | 0.80 | SMN1; SMN2 (0.43) | XDHALDH1A1TRPC6MAPTMEN1 | |
| SCHEMBL9547659 | 0.79 | XDH (0.53) | XDHALDH1A1GAADHODHMAPT | |
| SCHEMBL9185708 | 0.79 | XDH (0.53) | XDHALDH1A1GAADHODHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449676-A | Bronchodilator agents | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-09-12 | — | — | US | disclosed |
| EP-0510562-A1 | Pyridazines | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1992-10-28 | — | — | EP | disclosed |