Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258593 | 0.81 | GAA (0.41) | GAAMAPK1LMNAHTTALDH1A1 | |
| SCHEMBL7896518 | 0.78 | POLB (0.42) | GAAMAPK1LMNAHTTALDH1A1 | |
| SCHEMBL9869002 | 0.71 | ALDH1A1 (0.37) | GAAMAPK1LMNAHTTALDH1A1 | |
| SCHEMBL27309896 | 0.71 | POLB (0.39) | GAAMAPK1LMNAHTTALDH1A1 | |
| SCHEMBL15833455 | 0.67 | MGLL (0.48) | LMNAALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL9251387 | 0.67 | GAA (0.37) | GAAMAPK1LMNAHTTALDH1A1 | |
| SCHEMBL28674470 | 0.66 | MAPK1 (0.58) | MAPK1LMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL9175170 | 0.66 | ALDH1A1 (0.38) | GAAMAPK1LMNAHTTALDH1A1 | |
| SCHEMBL9171205 | 0.66 | GAA (0.49) | GAAMAPK1LMNAHTTALDH1A1 | |
| SCHEMBL9254724 | 0.65 | PIK3CA (0.35) | GAAMAPK1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135928-A | Treating angina, gastrointesinal disorders; antiinflammatory agents; antiulcer, analgesics; sedatives | EGIS GYOGYSZERGYAR (HU) | 1992-08-04 | — | — | US | disclosed |