Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 3/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251387 | 0.80 | GAA (0.37) | ALDH1A1KDM4EGAAMAPK1HTT | |
| SCHEMBL9660846 | 0.71 | GAA (0.42) | ALDH1A1KDM4EGAAMAPK1HTT | |
| SCHEMBL9258593 | 0.69 | GAA (0.41) | ALDH1A1KDM4EGAAMAPK1HTT | |
| SCHEMBL9250021 | 0.68 | GAA (0.36) | ALDH1A1KDM4EGAAMAPK1HTT | |
| SCHEMBL9175170 | 0.68 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAMAPK1HTT | |
| SCHEMBL7896518 | 0.67 | POLB (0.42) | ALDH1A1KDM4EGAAMAPK1HTT | |
| SCHEMBL9250855 | 0.65 | GAA (0.35) | ALDH1A1KDM4EGAAHTTHPGD | |
| SCHEMBL9168729 | 0.64 | POLB (0.35) | ALDH1A1KDM4EGAAHTTHPGD | |
| SCHEMBL9843398 | 0.64 | HRH4 (0.38) | — | |
| SCHEMBL27309896 | 0.63 | POLB (0.39) | ALDH1A1KDM4EGAAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3246282-A | — | — | None | — | — | JP | disclosed |
| JP-H03246282-A | TRIAZOLYLHYDRAZIDE DERIVATIVE, ITS PRODUCTION, COMPOSITION CONTAINING THE DERIVATIVE AS ACTIVE INGREDIENT FOR ANGINA PECTORIS OR GASTRIC ULCER AND PRODUCTION OF THE COMPOSITION | EGYT GYOGYSZERVEGYESZETI GYAR | 1991-11-01 | — | — | JP | disclosed |