Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258704 | 0.91 | HDAC1 (0.40) | ITGB3ITGA2BTYMSF10HDAC1 | |
| SCHEMBL9258892 | 0.89 | ITGB3 (0.39) | ITGB3ITGA2BTYMSF10 | |
| SCHEMBL9253735 | 0.84 | F10 (0.38) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9254490 | 0.83 | F10 (0.38) | ITGB3ITGA2BF10 | |
| SCHEMBL9255778 | 0.83 | ITGB3 (0.37) | ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL9568476 | 0.80 | TMPRSS15 (0.34) | ITGB3ITGA2BF10HDAC1F2 | |
| SCHEMBL9254911 | 0.79 | F7 (0.37) | ITGB3ITGA2BF10F2PLG | |
| SCHEMBL9255039 | 0.79 | S1PR1 (0.43) | ITGB3ITGA2BF10PLAU | |
| SCHEMBL9256974 | 0.77 | ITGB3 (0.51) | ITGB3ITGA2BF10F2PLG | |
| SCHEMBL9253132 | 0.77 | ITGB3 (0.51) | ITGB3ITGA2BF10F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |