Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254946 | 0.85 | GLA (0.45) | NQO2CTSBRAB9AL3MBTL1CYP1A1 | |
| SCHEMBL9254180 | 0.75 | CTSV (0.52) | RAB9A | |
| SCHEMBL9250550 | 0.70 | KMT2A (0.57) | RAB9ACYP1A2 | |
| SCHEMBL9251528 | 0.70 | CTSV (0.46) | RAB9A | |
| SCHEMBL9641920 | 0.66 | MAPT (0.47) | ELANECTSBRAB9AL3MBTL1CYP1A2 | |
| SCHEMBL3888294 | 0.65 | L3MBTL1 (0.55) | ELANECTSBRAB9AL3MBTL1 | |
| Formaldehyde SCHEMBL28320418 | 0.64 | RAB9A (0.51) | ELANECTSBRAB9AL3MBTL1 | |
| SCHEMBL15141642 | 0.64 | MAPT (0.43) | RAB9AL3MBTL1 | |
| SCHEMBL1770511 | 0.62 | POLB (0.47) | RAB9AL3MBTL1 | |
| SCHEMBL31058043 | 0.62 | POLB (0.47) | RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393756-A | Treating rheumatoid arthritis or osteoarthritis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-02-28 | — | — | US | disclosed |