Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351052 | 0.93 | POLB (0.35) | NR1I2POLBALOX5PTGS2NPC1 | |
| SCHEMBL769483 | 0.90 | POLB (0.37) | NR1I2POLBALOX5PTGS2NPC1 | |
| SCHEMBL29357045 | 0.90 | POLB (0.37) | NR1I2POLBALOX5PTGS2NPC1 | |
| SCHEMBL9265339 | 0.89 | KMT2A (0.37) | NR1I2POLBNPC1RAB9AHSP90AA1 | |
| SCHEMBL9263512 | 0.89 | NR1I2 (0.36) | NR1I2POLBALOX5PTGS2NPC1 | |
| SCHEMBL9265042 | 0.89 | NR1I2 (0.36) | NR1I2POLBNPC1RAB9A | |
| SCHEMBL7785455 | 0.85 | NPC1 (0.35) | POLBALOX5PTGS2NPC1RAB9A | |
| SCHEMBL23636578 | 0.81 | ACSS2 (0.38) | POLBALOX5PTGS2NPC1RAB9A | |
| SCHEMBL9257974 | 0.81 | NPC1 (0.31) | NPC1RAB9AHSP90AA1 | |
| SCHEMBL21586972 | 0.81 | POLB (0.37) | POLBPTGS2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599269-A1 | Compositions comprising sulfur-containing derivatives of hydroxyphenylbenzotriazole and process therefor | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-01 | — | — | EP | claimed |
| US-5410071-A | Sulfiding with a thiophenolic compound or a thiophenolate in a polar solvent to form a stabilizers for polyphenylene sulfide against UV radiation | PHILLIPS PETROLEUM COMPANY (US) | 1995-04-25 | — | — | US | disclosed |
| US-5319091-A | Contacting sulfur-containing aromatic compound with hydroxyphenylbenzotriazole derivative in presence of polar organic compound, oxidizing formed aryl sulfide derivative to sulfone, sulfoxide or mixtures | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0599269-A1 | Compositions comprising sulfur-containing derivatives of hydroxyphenylbenzotriazole and process therefor | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5274015-A | And a polyarylene sulfide polymer | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| US-5268450-A | Reating sodium hydrosulfide with a sulfur containing hydroxyphenylbenztriazole | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-07 | — | — | US | disclosed |