Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259467 | 1.00 | CTSK (0.41) | CTSKCTSLPTGDRPTGDR2PLA2G1B | |
| SCHEMBL9263608 | 0.86 | CTSK (0.41) | CTSKL3MBTL1DDB1CRBNMEN1 | |
| SCHEMBL9259858 | 0.86 | MTNR1A (0.45) | CTSKDDB1CRBNNPC1RAB9A | |
| SCHEMBL9259854 | 0.86 | MTNR1A (0.45) | CTSKDDB1CRBNNPC1RAB9A | |
| SCHEMBL9263612 | 0.86 | CTSK (0.41) | CTSKL3MBTL1DDB1CRBNMEN1 | |
| SCHEMBL9263516 | 0.85 | HPGD (0.45) | CTSKPTGDRPTGDR2PLA2G1BTSHR | |
| SCHEMBL9263521 | 0.85 | HPGD (0.45) | CTSKPTGDRPTGDR2PLA2G1BTSHR | |
| SCHEMBL9598230 | 0.85 | L3MBTL1 (0.44) | CTSKCTSLPTGDRPTGDR2TSHR | |
| SCHEMBL9598226 | 0.85 | L3MBTL1 (0.44) | CTSKCTSLPTGDRPTGDR2TSHR | |
| SCHEMBL9263327 | 0.84 | SLC6A3 (0.41) | L3MBTL1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476944-A | Inhibitors or stimulators of superoxide generation; may also inhibit cyclooxygenase and/or 5-lipoxygenase; useful in therapeutic or prophylactic treatment of disease conditions | G. D. SEARLE & CO. (US) | 1995-12-19 | — | — | US | disclosed |
| EP-0613463-A1 | DERIVATIVES OF CYCLIC PHENOLIC THIOETHERS AS INHIBITORS OR STIMULATORS OF SUPEROXIDE GENERATION | G.D. SEARLE & CO. (US) | 1994-09-07 | — | — | EP | disclosed |
| WO-1993010087-A1 | DERIVATIVES OF CYCLIC PHENOLIC THIOETHERS AS INHIBITORS OR STIMULATORS OF SUPEROXIDE GENERATION | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |