Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.66 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.66 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.66 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PLK1 | P53350 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567716 | 0.81 | CYP3A4 (0.44) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL6203515 | 0.81 | ALDH1A1 (0.68) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL994270 | 0.79 | ALDH1A1 (0.66) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| Chloralin SCHEMBL455937 | 0.79 | CYP3A4 (1.00) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL9316398 | 0.79 | GPR35 (0.66) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL11444409 | 0.79 | ALDH1A1 (0.66) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL9015339 | 0.79 | ALDH1A1 (0.82) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL8187684 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL7836515 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL11814312 | 0.78 | ALDH1A1 (0.63) | ALDH1A1CYP3A4TSHRTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287329-B1 | Chromogenic cryptahemispherands useful in detecting electrolytes | MILES INC (US) | 1993-12-08 | — | — | EP | claimed |
| US-5177221-A | Chromogenic hemispherands and their preparation | MILES INC. (US) | 1993-01-05 | — | — | US | claimed |
| US-5011924-A | Measurement Of Ions | TECHNICON INSTRUMENTS CORPORATION (US) | 1991-04-30 | — | — | US | claimed |
| US-4992381-A | Method of detecting electrolytes in an aqueous test sample using chromogenic hemispherands and test device therefor | TECHNICON INSTRUMENTS CORPORATION (US) | 1991-02-12 | — | — | US | claimed |
| EP-0371992-A1 | IONOPHORES AS REAGENTS FOR DETECTING IONS. | ALLIED SIGNAL INC (US) | 1990-06-13 | — | — | EP | claimed |
| US-4859606-A | Method for detecting cations in a test sample utilizing chromogenic cryptahemispherands | TECHNICON INSTRUMENTS CORPORATION (US) | 1989-08-22 | — | — | US | claimed |
| WO-1989000997-A1 | IONOPHORES AS REAGENTS FOR DETECTING IONS | ALLIED-SIGNAL INC. (US) | 1989-02-09 | — | — | WO | claimed |
| EP-0287330-A2 | Chromogenic hemispherands useful for detecting electrolytes | Bayer Corporation (US) | 1988-10-19 | — | — | EP | claimed |
| EP-0287329-A2 | Chromogenic cryptahemispherands useful in detecting electrolytes | Bayer Corporation (US) | 1988-10-19 | — | — | EP | claimed |
| US-5439828-A | Fluorgenic and chomogenic three-dimensional ionophores as selective reagents for detecting ions in biological fluids | ALLIEDSIGNAL INC. (US) | 1995-08-08 | — | — | US | disclosed |
| EP-0287329-B1 | Chromogenic cryptahemispherands useful in detecting electrolytes | MILES INC (US) | 1993-12-08 | — | — | EP | disclosed |
| US-5177221-A | Chromogenic hemispherands and their preparation | MILES INC. (US) | 1993-01-05 | — | — | US | disclosed |
| US-5162525-A | FLUOROGENIC AND CHROMOGENIC THREE-DIMENSIONAL IONOPHORES AS SELECTIVE REAGENTS FOR DETECTING IONS IN BIOLOGICAL FLUIDS | ALLIED-SIGNAL INC. (US) | 1992-11-10 | — | — | US | disclosed |
| US-5011924-A | Measurement Of Ions | TECHNICON INSTRUMENTS CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-4992381-A | Method of detecting electrolytes in an aqueous test sample using chromogenic hemispherands and test device therefor | TECHNICON INSTRUMENTS CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0371992-A1 | IONOPHORES AS REAGENTS FOR DETECTING IONS. | ALLIED SIGNAL INC (US) | 1990-06-13 | — | — | EP | disclosed |
| WO-1989000997-A1 | IONOPHORES AS REAGENTS FOR DETECTING IONS | ALLIED-SIGNAL INC. (US) | 1989-02-09 | — | — | WO | disclosed |
| EP-0287330-A2 | Chromogenic hemispherands useful for detecting electrolytes | Bayer Corporation (US) | 1988-10-19 | — | — | EP | disclosed |
| EP-0287329-A2 | Chromogenic cryptahemispherands useful in detecting electrolytes | Bayer Corporation (US) | 1988-10-19 | — | — | EP | disclosed |
| US-4117167-A | INSECTICIDES, ACARICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | disclosed |