Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 6/20 | 0.39 |
| ▸ | CTSK | P43235 | 5/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549571 | 0.85 | CTSS (0.44) | CTSSCTSK | |
| SCHEMBL7273450 | 0.85 | SLC7A5 (0.43) | CTSSCTSK | |
| SCHEMBL6548736 | 0.85 | ITGA4 (0.44) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6952234 | 0.84 | MAOB (0.44) | MAOBCTSSCTSKPRSS1CTSG | |
| SCHEMBL7273304 | 0.82 | ALOX5 (0.36) | CTSSCTSK | |
| SCHEMBL8392929 | 0.77 | ATM (0.45) | CTSSCTSKCTSLCTSB | |
| SCHEMBL9321962 | 0.77 | ATM (0.45) | CTSSCTSKCTSLCTSB | |
| SCHEMBL11651226 | 0.77 | ATM (0.45) | CTSSCTSKCTSLCTSB | |
| SCHEMBL25336645 | 0.76 | LDHA (0.36) | CTSSCTSK | |
| SCHEMBL25336642 | 0.76 | LDHA (0.36) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5412145-A | P2'-modified hydroxamic acid collagenase inhibitors | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1995-05-02 | — | — | US | disclosed |
| US-5300674-A | P2'-modified hydroxamic acid collagenase inhibitors | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-04-05 | — | — | US | disclosed |