Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260001 | 0.84 | F2 (0.37) | RAB9A | |
| SCHEMBL9259956 | 0.78 | LMNA (0.37) | POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7347372 | 0.71 | RAB9A (0.37) | POLBKMT2AMEN1TRPM8TSHR | |
| SCHEMBL9440351 | 0.71 | RAB9A (0.37) | POLBKMT2ATSHRRAB9AALDH1A1 | |
| SCHEMBL6979118 | 0.70 | ALDH1A1 (0.33) | POLBKMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL6972945 | 0.70 | PARP1 (0.49) | POLBKMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL7420630 | 0.70 | KMT2A (0.39) | POLBKMT2AMEN1L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL7351854 | 0.69 | PARP1 (0.48) | POLBKMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL9559149 | 0.67 | LMNA (0.41) | POLBKMT2AMEN1TSHRRAB9A | |
| SCHEMBL9559156 | 0.67 | MAPT (0.37) | KMT2AMEN1L3MBTL1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |