Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259952 | 0.84 | CYP2C19 (0.41) | LMNAHTTSMN1; SMN2KDM4ECYP2C19 | |
| SCHEMBL9260010 | 0.78 | POLB (0.35) | SMN1; SMN2RAB9APOLB | |
| SCHEMBL7361744 | 0.72 | RAB9A (0.62) | LMNAHTTSMN1; SMN2KDM4ECYP2C19 | |
| SCHEMBL9425991 | 0.68 | KLK5 (0.40) | CYP2C19RAB9A | |
| SCHEMBL6979118 | 0.68 | ALDH1A1 (0.33) | SMN1; SMN2RAB9APOLB | |
| SCHEMBL9559013 | 0.67 | GAA (0.44) | LMNAHTTSMN1; SMN2KDM4ECYP2C19 | |
| SCHEMBL9559001 | 0.67 | LMNA (0.42) | LMNAHTTSMN1; SMN2KDM4ECYP2C19 | |
| SCHEMBL9257997 | 0.67 | GAA (0.37) | LMNAHTTSMN1; SMN2KDM4ECYP2C19 | |
| SCHEMBL9559016 | 0.66 | GAA (0.42) | LMNAHTTSMN1; SMN2KDM4ECYP2C19 | |
| SCHEMBL9559004 | 0.66 | LMNA (0.42) | LMNAKDM4ERAB9AFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |