Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279948 | 0.88 | KMT2A (0.51) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL11529174 | 0.88 | LMNA (0.57) | ALDH1A1SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL4243805 | 0.87 | ATM (0.42) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL811749 | 0.87 | MEN1 (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL8398078 | 0.87 | LOXL2 (0.43) | ALDH1A1SMN1; SMN2TSHRCA2LMNA | |
| SCHEMBL28291826 | 0.87 | HSD17B1 (0.43) | ALDH1A1SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL347302 | 0.84 | PSIP1 (0.54) | ALDH1A1SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL8393959 | 0.84 | HDAC8 (0.42) | ALDH1A1SMN1; SMN2CA1CA2CA9 | |
| SCHEMBL27626946 | 0.84 | HDAC4 (0.40) | ALDH1A1SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL14228194 | 0.83 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438142-A | Tris(hydroxyphenyl)ethanes having ketone, bromine, sulfonate, or amine groups as condensation polymer modifiers; photostabilizers, flame retardants, discoloration inhibitors, antisoilants, antioxidants | HOECHST CELANESE CORP. (US) | 1995-08-01 | — | — | US | disclosed |
| US-4405808-A | FROM ACETIC ACID AND OLEFIN IN PRESENCE OF STEAM AND AROMATIC DISULFONIC ACID CATALYST | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-09-20 | — | — | US | disclosed |