Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261565 | 0.88 | LMNA (0.48) | LMNAPOLBADORA1ADORA2BMEN1 | |
| SCHEMBL9267445 | 0.87 | ADORA1 (0.41) | LMNAPOLBADORA1ADORA2BKMT2A | |
| SCHEMBL9263087 | 0.87 | GABRA1 (0.54) | LMNAPOLBADORA1ADORA2BKDM4E | |
| SCHEMBL9256941 | 0.86 | LMNA (0.46) | LMNAPOLBMEN1KMT2APTGDR2 | |
| SCHEMBL9261346 | 0.83 | PTGDR2 (0.45) | LMNAPOLBADORA1MEN1KMT2A | |
| SCHEMBL9261406 | 0.80 | KDM4E (0.43) | LMNAPOLBADORA1ADORA2BMEN1 | |
| SCHEMBL9262280 | 0.80 | KDM4E (0.46) | ADORA1ADORA2BPTGDR2KDM4EMAPT | |
| SCHEMBL9265830 | 0.79 | ALDH1A1 (0.41) | LMNAPOLBADORA1ADORA2BMEN1 | |
| SCHEMBL9262785 | 0.78 | PTGER1 (0.39) | LMNAPOLBADORA1ADORA2BMEN1 | |
| SCHEMBL9264676 | 0.78 | GABRA1 (0.46) | LMNAPOLBMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |