Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264825 | 0.90 | LMNA (0.41) | LMNAPOLBTRPM2KDM4ERAB9A | |
| SCHEMBL9261260 | 0.88 | GABRA1 (0.52) | LMNATRPM2KDM4EALBCYP3A4 | |
| SCHEMBL9261373 | 0.86 | LMNA (0.47) | LMNAPOLBKDM4EGFERPTGDR2 | |
| SCHEMBL9416616 | 0.75 | POLB (0.44) | LMNAPOLBKDM4EGFERPTGDR2 | |
| SCHEMBL9258551 | 0.75 | TRPM2 (0.37) | LMNAPOLBTRPM2KDM4EGFER | |
| SCHEMBL9261565 | 0.74 | LMNA (0.48) | LMNAPOLBKDM4EPTGDR2MAPT | |
| SCHEMBL8879204 | 0.74 | SLC2A1 (0.42) | LMNAPOLBTRPM2KDM4EGFER | |
| SCHEMBL9267445 | 0.74 | ADORA1 (0.41) | LMNAPOLBKDM4EKMT2AALB | |
| SCHEMBL9263087 | 0.74 | GABRA1 (0.54) | LMNAPOLBKDM4EALBCYP3A4 | |
| SCHEMBL8864505 | 0.72 | ADORA2B (0.38) | TRPM2KDM4EGFERRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |