Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261406 | 0.95 | KDM4E (0.43) | KDM4EMAPTPTGDR2ADORA1ALDH1A1 | |
| SCHEMBL9265963 | 0.89 | TSPO (0.46) | KDM4EHPGDGABRA2GABRB2 | |
| SCHEMBL9261380 | 0.89 | MAPT (0.41) | KDM4EMAPTADORA1ADORA2BSHMT1 | |
| SCHEMBL9264404 | 0.87 | KDM4E (0.41) | KDM4EMAPTADORA1ADORA2BHTT | |
| SCHEMBL9264565 | 0.85 | ADORA2B (0.42) | KDM4EMAPTADORA1ADORA2BSHMT1 | |
| SCHEMBL9257923 | 0.85 | TSPO (0.46) | KDM4EHPGDADORA2BGABRA2GABRB2 | |
| SCHEMBL9261565 | 0.83 | LMNA (0.48) | KDM4EMAPTPTGDR2ADORA1ALDH1A1 | |
| SCHEMBL9261346 | 0.82 | PTGDR2 (0.45) | KDM4EPTGDR2ADORA1ALDH1A1CYP2C9 | |
| SCHEMBL9261373 | 0.80 | LMNA (0.47) | KDM4EMAPTPTGDR2ADORA1ADORA2B | |
| SCHEMBL9263544 | 0.75 | HPGD (0.40) | KDM4EMAPTADORA1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |