Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264212 | 0.85 | ADORA3 (0.41) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL9416616 | 0.81 | POLB (0.44) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL9264131 | 0.80 | KMT2A (0.47) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL9262552 | 0.71 | NR4A2 (0.45) | POLBMEN1KMT2AKDM4ELMNA | |
| SCHEMBL9261073 | 0.70 | KMT2A (0.45) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL9416648 | 0.69 | ADORA3 (0.44) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL16021113 | 0.65 | ADORA3 (0.49) | TP53MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL9267445 | 0.65 | ADORA1 (0.41) | POLBKMT2AKDM4ELMNAHPGD | |
| SCHEMBL12850767 | 0.65 | MAPT (0.43) | POLBTP53MEN1KMT2AGAA | |
| SCHEMBL20893121 | 0.64 | ADORA2A (0.47) | POLBTP53MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |
| EP-0607076-A1 | 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity | SYNTHELABO (FR) | 1994-07-20 | — | — | EP | disclosed |