Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258465 | 0.81 | HSD11B1 (0.40) | HSD11B1TRPA1CNR1CNR2ALDH1A1 | |
| SCHEMBL9258898 | 0.79 | TRPA1 (0.45) | TRPA1ADORA2AADORA1TSHRCHRM1 | |
| SCHEMBL12945592 | 0.78 | ADORA2A (0.43) | TRPA1ADORA2AADORA1CNR1CNR2 | |
| SCHEMBL21652229 | 0.77 | AHR (0.44) | HSD11B1TRPA1ALDH1A1TSHRTDP1 | |
| SCHEMBL12597777 | 0.76 | PTGS2 (0.47) | TRPA1CNR1CNR2ALDH1A1TSHR | |
| SCHEMBL8819364 | 0.75 | ADORA1 (0.41) | HSD11B1ADORA2AADORA1CNR1CNR2 | |
| SCHEMBL21652293 | 0.74 | PDK2 (0.40) | HSD11B1TRPA1CNR1CNR2ALDH1A1 | |
| SCHEMBL28582164 | 0.73 | TRPA1 (0.43) | HSD11B1TRPA1ALDH1A1TSHRTDP1 | |
| SCHEMBL25815497 | 0.72 | ENPP3 (0.44) | ADORA2AADORA1CNR1CNR2ALDH1A1 | |
| SCHEMBL9288003 | 0.72 | CHRM1 (0.43) | TRPA1ADORA2AADORA1CHRM1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | BACE1, STS, APP | HSD11B1 702/4885TRPA1 3202/4885ADORA2A 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.