Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM2 | P31350 | 3/20 | 0.52 |
| ▸ | RRM1 | P23921 | 1/20 | 0.52 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.52 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 3/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | CTH | P32929 | 2/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9289701 | 1.00 | RRM2 (0.52) | RRM2RRM1RRM2BCISD1NCOA3 | |
| SCHEMBL6676551 | 0.84 | RRM2 (0.73) | RRM2RRM1RRM2BCISD1NCOA3 | |
| SCHEMBL6676547 | 0.84 | RRM2 (0.73) | RRM2RRM1RRM2BCISD1NCOA3 | |
| SCHEMBL9459217 | 0.79 | KMT2A (0.53) | KDM4EGAAKMT2AMAPTRAB9A | |
| SCHEMBL9151853 | 0.79 | KMT2A (0.53) | KDM4EGAAKMT2AMAPTRAB9A | |
| SCHEMBL9768958 | 0.74 | ALDH1A1 (0.39) | RRM2RRM1RRM2BCISD1NCOA3 | |
| SCHEMBL13826730 | 0.74 | NPC1 (0.68) | KDM4EHTTOPRK1KMT2AL3MBTL1 | |
| SCHEMBL19668661 | 0.74 | ALDH1A1 (0.42) | RRM2RRM1RRM2BCISD1NCOA3 | |
| SCHEMBL9273907 | 0.74 | KMT2A (0.39) | RRM2RRM1RRM2BCISD1NCOA3 | |
| SCHEMBL14075814 | 0.73 | CTRC (0.74) | KDM4EHTTGAAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021822-A1 | PYRIDINIUM COMPOUNDS | GEORGIA TECH RESEARCH CORPORATION (US) | 1995-08-17 | — | — | WO | disclosed |
| EP-0643697-A4 | QUATERNARY PYRIDINIUM COMPOUNDS. | — | 1995-04-12 | — | — | EP | disclosed |
| EP-0643697-A1 | QUATERNARY PYRIDINIUM COMPOUNDS | GEORGIA TECH RESEARCH CORPORATION (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5290942-A | Acetylcholinesterase inhibitors | GEORGIA TECH RESEARCH CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |
| WO-1993024459-A1 | QUATERNARY PYRIDINIUM COMPOUNDS | GEORGIA TECH RESEARCH CORPORATION (US) | 1993-12-09 | — | — | WO | disclosed |
| US-5206371-A | Acetylcholinesterase inhibitor | GEORGIA TECH RESEARCH CORPORATION (US) | 1993-04-27 | — | — | US | disclosed |
| US-5180831-A | Acetylcholinesterase Inhibitors | GEORGIA TECH RESEARCH CORPORATION (US) | 1993-01-19 | — | — | US | disclosed |